One of the key advantages of large bore aspiration catheters is their ability to restore blood flow to the brain quickly. In some cases, the procedure can be completed in as little as 30 minutes. This is in contrast to standard medical therapy, which can take several hours to take effect. The faster the blood flow is restored, the less damage is done to the brain tissue, improving the patient's chances of a full recovery.

The use of large bore aspiration catheters has also greatly expanded the treatment window for acute ischemic stroke. Traditionally, mechanical thrombectomy could only be performed within the first 6 hours of symptom onset. However, recent studies have shown that the procedure can be performed up to 24 hours after onset in select patients. This allows for more patients to receive optimal stroke care, even those who may not have presented within the traditional treatment window.